If Machu Picchu and Rio de Janeiro are already on your list—but you’re craving something less crowded and more immersive—you’re in the right place. South America is filled with iconic destinations, but beyond the bucket-list spots lies a tapestry of underrated towns, cities, and regions where culture, nature, and authenticity shine.
This list is for the curious traveler looking to escape the crowds, discover local flavor, and connect with the real South America—without sacrificing safety, beauty, or memorable experiences.
Sucre, Bolivia
Known for: Colonial architecture, whitewashed buildings, student energy
Why people love it: Often overshadowed by La Paz, Sucre is Bolivia’s constitutional capital and a UNESCO World Heritage site. It’s clean, calm, and full of history—perfect for travelers seeking a slower pace and a real cultural immersion.
Safety: Safe and relaxed atmosphere
Top attractions: Plaza 25 de Mayo, Tarabuco Market, Recoleta Monastery
Best time to visit: May to October for dry, sunny weather
Valparaíso, Chile
Known for: Colorful hills, street art, bohemian vibe
Why people love it: This seaside port city is a creative haven for artists and poets. With its steep hills, vibrant murals, and funiculars, Valparaíso feels like a South American San Francisco—with Chilean flavor.
Safety: Safe in tourist areas; stay alert in busy public spaces
Top attractions: La Sebastiana (Neruda’s house), Ascensor Artillería, Cerro Concepción
Best time to visit: November to March for warm weather and open-air events
Cafayate, Argentina
Known for: Wine country, red rock canyons, artisan vibes
Why people love it: A quieter, more rustic counterpart to Mendoza, Cafayate is a hidden gem for wine lovers and hikers alike. Sip Torrontés, wander through canyons, and experience Argentina off the beaten path.
Safety: Very safe, especially for solo travelers
Top attractions: Quebrada de las Conchas, local wineries, Museo de la Vid y el Vino
Best time to visit: March to May or September to November for mild weather
Mompox, Colombia
Known for: Colonial charm, riverfront tranquility, literary history
Why people love it: Tucked away on the Magdalena River, Mompox feels like a magical realist novel come to life. It’s peaceful, historic, and untouched by mass tourism.
Safety: Generally safe; best to travel by trusted transport
Top attractions: Santa Barbara Church, river tours, cemetery art
Best time to visit: December to March for drier days
Cuenca, Ecuador
Known for: Old-world charm, expat community, cobbled streets
Why people love it: With its pleasant climate, well-preserved colonial core, and creative energy, Cuenca is a favorite among travelers seeking a safe and scenic cultural base.
Safety: Very safe and walkable
Top attractions: New Cathedral, Cajas National Park, artisan markets
Best time to visit: June to September for drier, cooler conditions
Jericoacoara, Brazil
Known for: Dune landscapes, laid-back beach life, windsurfing
Why people love it: Remote, rustic, and relaxing—“Jeri” is a barefoot paradise that takes effort to reach, but rewards you with unreal sunsets, no streetlights, and a chill vibe.
Safety: Safe, with some minor petty theft in high season
Top attractions: Duna do Pôr do Sol, Lagoa do Paraíso, Pedra Furada
Best time to visit: July to December for dry season and wind sports
Salento, Colombia
Known for: Coffee culture, lush mountains, colorful facades
Why people love it: Gateway to the Cocora Valley and Colombia’s coffee triangle, Salento is small but rich in flavor, nature, and local hospitality.
Safety: Very safe and welcoming to tourists
Top attractions: Cocora Valley hike, coffee farms, Calle Real
Best time to visit: December to March or June to August
Paraty, Brazil
Known for: Cobblestone streets, cachaça distilleries, island hopping
Why people love it: This coastal colonial town is a dreamy mix of jungle and ocean. It’s an artsy escape surrounded by waterfalls, hiking trails, and island-filled bays.
Safety: Safe in tourist areas; avoid deserted alleys at night
Top attractions: Historic center, boat tours, Serra da Bocaina
Best time to visit: April to June and August to October for pleasant weather
Chachapoyas, Peru
Known for: Ancient ruins, cloud forests, pre-Incan history
Why people love it: Home to Kuelap (the “Machu Picchu of the North”), this region is rugged, green, and steeped in mystery. Perfect for those who want archaeology without the crowds.
Safety: Generally safe; travel with a guide for rural areas
Top attractions: Kuelap Fortress, Gocta Falls, Karajía sarcophagi
Best time to visit: May to September for dry season hiking
Bariloche, Argentina
Known for: Alpine lakes, Swiss-style architecture, chocolate
Why people love it: Nestled in Patagonia’s lake district, Bariloche blends outdoor adventure with alpine aesthetics. Think hiking, kayaking, and indulging in chocolate shops.
Safety: Very safe; active outdoor scene
Top attractions: Cerro Campanario, Circuito Chico, Nahuel Huapi Lake
Best time to visit: December to March for summer hikes; July for skiing
Final Thought
Whether you’re sipping wine in Argentina’s high-altitude valleys, wandering colorful port towns in Chile, or stargazing in Colombia’s coffee hills, these lesser-known destinations show South America’s softer, deeper side. Skip the crowds, connect with culture, and fall in love with the road less traveled.